After Earth is torn apart by religious differences and the human race teeters on the edge of extinction, an atheistic android architect sends two of his creations, Mother and Father, to start a peaceful, godless colony on the planet Kepler-22b. Raised by Wolves follows Mother and Father as they attempt to raise human children in this mysterious virgin land, a treacherous and difficult task that's jeopardized by the arrival of the Mithraic, a deeply devout religious order of surviving humans. As the androids make contact with this zealous and dangerous people, they struggle to control the beliefs of their fiercely self-determining children.