A severely broken arm reveals a bizarre case of bone loss and ends the comeback plans of major league pitcher Hank Wiggen. House suspects Hank is lying about using steroids as his condition worsens. When Hank's kidneys start to fail, his wife offers to donate hers, but she would have to abort her early pregnancy. Forced into an impossible solution and admitting failure as an addict, Hank tries to take his own life. House and his team must soon isolate and fix the problem if this pitcher's life and career can be saved. Meanwhile, Foreman dates a pharmaceutical representative, and House is stuck with two tickets and goes on a "date" with Cameron to a monster truck rally.