A new form of STD labeled “The Hand of God” causes the infected to die and return as the flesh eating living dead. The only difference is males who come back are sexually aggressive and spread the virus by any means necessary. Young musician, Paul Rhodes, contracts the disease after sleeping with a woman while his wife is out of town. He locks himself in his apartment as his body begins to deteriorate into the living dead. Paul is forced to amputate pieces of himself as the infection spreads throughout his body while the outside world goes to hell. Paul wrestles with the guilt of his “sin” and journeys into madness as the virus tries to take control of him.