Most comedians start their careers doing Stand Up. However, some of the more gifted attempt to crossover to “legitimate” theater with varied results.

Here is a list of films where comedians managed to harness their energy to create some of the most memorable dramatic roles to ever grace the silver screen.

1. Whoopi Goldberg, The Color Purple
2. Lily Tomlin, Nashville
3. Sarah Silverman, I Smile Back
4. Bette Midler, The Rose
5. Bill Murray, Lost in Translation
6. Ben Stiller, Greenberg
7. Jamie Foxx, Ray
8. Mo’Nique, Precious
9. Jim Carrey, The Truman Show
10. Jenny Slate, Obvious Child
11. Richard Pryor, Blue Collar
12. Steve Martin, The Spanish Prisoner
13. Robin Williams, The Fisher King
14. Art Carney, Harry & Tonto
15. Jerry Lewis, The King of Comedy
16. Peter Sellers, Being There
17. Goldie Hawn, The Sugarland Express
18. Adam Sandler, Funny People
19. Eddie Murphy, Dreamgirls
20. Mary Tyler Moore, Ordinary People
21. Albert Brooks, Drive
22. Lucille Ball, Lured
23. Patton Oswalt, Big Fan
24. Tracey Ullman, Household Saints
25. Kristen Wiig, Welcome to Me
26. Roberto Benigni, Life Is Beautiful
27. Billy Crystal, Mr. Saturday Night
28. Steve Carell, The Big Short
29. John Leguizamo, Summer of Sam
30. Cloris Leachman, The Last Picture Show
31. Marlon Wayans, Requiem for a Dream
32. Maya Rudolph, Away We Go
33. Jason Segel, The End of the Tour
34. Seth Rogen, Steve Jobs
35. Dane Cook, Mr. Brooks
36. Chris Tucker, Silver Linings Playbook
37. Christopher Guest, Girlfriends
38. Dan Aykroyd, The House of Mirth
39. Will Ferrell, Everything Must Go
40. Jackie Gleason, The Hustler