In South London, mother and daughter extreme cleaners Maxine and Jasmine are called to a house that is bursting at the seams with decades of arts and crafts clutter. The owner is determined to clear some space but struggles to part with anything - leading to a frustrating job for the girls. In Crawley, sisters Yvonne and Angela are called to a job by Paula who suffers with anxiety and agoraphobia, and can no longer sleep in her bedroom while the living room is hidden under mountains of rubbish.