Eight women of various backgrounds, experiences and lifestyles are out on the road dealing the days responsibilities. We follow Nadine, the mother with a never-ending “To Do” list; Lyndsey, an inexperienced driver going to help a friend; Abby and Torry, a lesbian couple on a road trip to deal with problems in their relationship; Geena, struggling with her collapsing marriage; Lydia, fleeing her an abusive relationship; Chelsea, a young woman unaware of how few problems she has; and Erika, a pizza delivery person lost in a stagnant life. As all eight deal with their issues at hand they are, unknowingly, all destined to meet at the same location.